Top 10 Most Painful Diseases

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A diseased existence is worse than non-existence. It’d be highly unjustified to rate diseases as every suffering is impalpable by anyone other than the sufferer himself. The researchers devised scales to actually rate the amount of pain one suffers from and it’s solely on that basis that we have come to enlist some of the world’s most painful disease. God forbid you from experiencing them and we the immortal beings pray for the healthy existence of our readers while to those suffering from any of these, we wish a swift recovery.


10) Crohn Disease


Crohn Disease was recognized in the year 1932 by Dr. Burrill B. Crohn along with Dr. Leon Ginzburg and Dr. Gordon Oppenheimer. Crohn disease basically belongs to the group of Inflammatory Bowel Diseases or better known as IBDs. It causes inflammation of the gastro-intestinal tract. Thus, even normal bowel movements can be really excruciatingly painful.

Crohn disease’s symptoms are often confused with those of ulcerative colitis which is yet another Inflammatory Bowel Disease, as the symptoms of these two are very similar and both affects the gastro-intestinal tracts. However what marks the two different are the areas affected. While Crohn affects the end of the small bowel or the ileum and the fore areas of gastrointestinal tract or in worst cases the whole tract from mouth to anus.  Ulcerative Colitis is a little less harsh as it is limited to the colon region. Crohn can affect the entire thickness of the bowel wall.

9) Migraines


Out of every 4 people who suffer from headaches one could be the case of Migraine. In America alone, more than 28 million people have to go through the ordeal of migraine. The worst part about migraine pains are that it can be triggered by anything and without prior warning. That means you’d wake up fine and something a few hours later will trigger your migraine and your whole day will be gone trying to ease that pulsating pain. It literally robs you off the quality of life.

The most common symptoms associated with migraines are pulsating headaches (it feels like one of your nerves will burst), nausea, vomiting and light sensitivity (most of the patients suffering from migraines are told to retreat in a dark room as soon as possible). It is a chronic neurological disorder and can have an effect on half your brain. It can last up to 2 to 72 hours.

8) Arthritis


Arthritis is painful and moreover it is painful in 100 different ways. There are more than 100 forms of arthritis recognized till date. It is a form of joint disorder and the most common symptom is the inflammation of joints. The inflammation is followed by intense incessant pain localized to the joints that are fatigued.

Arthritis is one of the most common causes of disability. The patient not only suffers from inflammation and pain but in some cases, is robbed off his/her ability to even walk or function, especially movements that include using the joints (which includes almost all bodily movements). This disease is apparently so old that a mummy, named Ötzi, which may have been mummified in 3000 BC, was found out to be a death resultant of arthritis.

7) Appendicitis


Appendicitis is medical emergency that means no prior symptoms or warning akin to heart strokes and kidney stones, is experienced by the sufferer. Appendicitis is caused by inflammation of appendix and the only symptom is the severe abdominal pain.

The immediate symptoms may be pain, vomiting and fever and as the appendix swells the pain will move into a downward direction from the stomach-high.  Then, it can stay in the localized in the right lower quadrant. It can be cured by a surgical procedure called Appendicetomy through a Laparoscopic removal which is remotion of the infected appendix and the full recovery (in case the appendix had been ruptured) can take anywhere from six to eight weeks.

6) Hidradenitis suppurativa


Hidradenitis suppurativa is an extremely painful skin related disease which mainly affects the areas containing sweat or sebaceous glands that means the underarms, under-breasts, inner thighs and groin area. Although it’s a not contagious disease but popular perception is otherwise because it can cause clusters of abscess in the affected area or cysts which may appear in multiple locations over the body.

The size of these formation can be huge (the size of a tennis ball) in aggravated stage or small (marble or pea sized). These knots like cysts are extremely painful to touch and the inflammation sometime causes the abscess to erupt through incision that appears due to stretching of the skin.

5) Fibromyalgia


Fibromyalgia (fibro- tissues, myo- muscle and algos- pain) is described as the “central sensitization syndrome”. Out of every ten person who suffer from Fibromyalgia, nice are women. It could be a resultant of psychological, genetic, neurobiological or sometime environmental factors. Around the world about 3-5% of the population is believed to be suffering from Fibromyalgia. The disease is synonym with pain as the symptoms include chronic pain, muscle spasms, weakness, nerve pain and sleep disturbances.

The exact cause of this disease are still unknown though hypothetically the hyper reactivity of pain sensitive cells if oft blamed. This gives the Fibromyalgia patient a disadvantage when it comes to threshold of pain.

4) Kidney Stones


The condition of Kidney stones is also called renal calculus that literally translates into ‘Kidney Pebble’. Men are more prone to developing this crystal aggregation than their female counterparts. The shooting pain of Kidney stone is localized in the area between the ribs and the hip also called the flank.

Although it’s the occurrence of a stone that’s the real problem but first concern if the pain that accompanies it. It can be controlled using opioid or anti-inflammatory drugs that surpass the blood-brain barrier. The most common hallmark of Kidney stone is the excruciating and sporadic pain. It is observed to run in families. Nevertheless, diligent dietary measure can cut down one’s risk of developing Kidney stones.

3) Ebola


Ebola virus disease (EVD) or Ebola hemorrhagic fever (EHF) is caused by Ebola virus. The name is derived from Ebola River, where its causalities were first recorded. It is a type of a viral hemorrhagic fever and is almost alike to Marburg Disease.

It begins with influenza like symptoms and as the conditions aggravates the patient might suffer from chest pains, abdominal cramps, sore throat, headaches and could lead to coma. The unfortunate part is that till now there is no specific therapy yet approved by FDA for the disease caused by this particular virus. So the process is mainly about minimizing invasive procedure, electrolyte retention and other supportive procedures.

2) Cancer


It is often resonated that when a person suffers from cancer then s/he doesn’t suffer alone the entire family and friends suffer from it too.

The pain in cancer is caused by almost everything; the disease, the treatment and the post-treatment recuperating period. It pains when the tumor compresses or infiltrates the tissues, it is excruciating to undergo the treatment and diagnostic procedures, the hormones and processes that the human body undergoes to put up a fight against the tumor, the chemo and the radiotherapy, effects of which doesn’t end with the session. The pain can last a lot longer after the treatment.

1) Causalgia


Causalgia or the Complex Regional Pain Syndrome was also known as Reflex Sympathetic Dystrophy. It is also the most rarest and painful disease. In causalgia the arms and legs experience an incessant sense of aching and seething pain, the area discolor and develops a high degree of sensitivity. The pains gradually become worse as the situation aggravates.

Causalgia is concluded as a multifactorial disorder which includes neurogenic inflammation, extreme sensitivity and vasomotor dysfunction. The treatment of Causalgia is a complex one and involves intense therapy sessions, drugs and psychologic treatments. It can affect at any age however, the mean is 42. Women are more prone to Causalgia than their male counterparts.


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